Dendrimeric Guanidinoneomycin for Cellular Delivery of Bio-macromolecules
نویسندگان
چکیده
منابع مشابه
Cellular delivery of noncovalently-associated macromolecules by cell-penetrating peptides.
Cellular and nuclear delivery of biomolecules is limited by low membrane permeability. Cell-penetrating peptides (CPPs) can be covalently linked to cargos to improve cellular internalization. Our work indicates that arginine-rich CPPs are also able to interact with a variety of cargos, including DNA, RNA, proteins and nanomaterials, in a noncovalent manner and subsequently effect their delivery...
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ژورنال
عنوان ژورنال: ChemBioChem
سال: 2016
ISSN: 1439-4227
DOI: 10.1002/cbic.201600422